Differential Electrophysiological Coupling for Positive and Negative BOLD Responses during Unilateral Hand Movements
نویسندگان
چکیده
منابع مشابه
Differential electrophysiological coupling for positive and negative BOLD responses during unilateral hand movements.
The coupling between neural cellular activity and blood oxygen level-dependent (BOLD) signal is of critical importance to the interpretation of fMRI. Largely unknown, however, is the degree to which different neuronal events (i.e., excitation and inhibition) maintain or disrupt the neural-hemodynamic relationship, especially in humans. In the present study, we compared local electroencephalogra...
متن کاملHigh-Resolution fMRI Reveals Laminar Differences in Neurovascular Coupling between Positive and Negative BOLD Responses
The six cortical layers have distinct anatomical and physiological properties, like different energy use and different feedforward and feedback connectivity. It is not known if and how layer-specific neural processes are reflected in the fMRI signal. To address this question we used high-resolution fMRI to measure BOLD, CBV, and CBF responses to stimuli that elicit positive and negative BOLD si...
متن کاملInvestigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7 T
Decreases in stimulus-dependent blood oxygenation level dependent (BOLD) signal and their underlying neurovascular origins have recently gained considerable interest. In this study a multi-echo, BOLD-corrected vascular space occupancy (VASO) functional magnetic resonance imaging (fMRI) technique was used to investigate neurovascular responses during stimuli that elicit positive and negative BOL...
متن کاملDifferences in neurovascular coupling in areas with positive and negative BOLD signal
Introduction While the dynamics and mechanism of the positive BOLD response have been well studied, much less is known about the mechanism of the negative BOLD response. Although the negative BOLD response is related to decreases in neural activity [1] and in CBF [2], the temporal dynamics differ from that of the positive BOLD signal [1]. Here, we studied the properties of the negative BOLD res...
متن کاملThe electrophysiological basis of negative BOLD in default mode network
Introduction: The default mode network (DMN) [1], which includes medial prefrontal cortex (MPFC), posterior cingulate cortex (PCC), precuneus and the left and right inferior parietal lobules (IPLs), has been widely investigated using fMRI. The network is characterised by high intrinsic correlation between BOLD signals measured at separate network nodes in the resting state, implying functional ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2011
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5312-10.2011